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Anticoagulation Therapy

by Ozcan Basaran

Intechopen

Hardback or Cased Book 152 pages Sep 08, 2016

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The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
Author:
Ozcan Basaran
Publisher:
Intechopen
Publication Date:
Sep 08, 2016
Number of pages:
152 pages
Binding:
Hardback or Cased Book
ISBN-10:
9535126660
ISBN-13:
9789535126669